Biol. Pharm. Bull. 28(1) 27—31 (2005)

in Korea, is a mushroom belonging to the Hymenochaetaceae basidiomycetes and also found mainly in tropical America, Africa and Asian countries. Overall, PL was reported to be a medicinal mushroom with anti-tumor activity, protective effect on liver damage, immunomodulatory action, antiangiogenic and antioxidant activity. The hot aqueous extract of PL inhibited the growth of sarcoma 180 to about 96.7% of untreated control in ICR mice. Of different Phellinus species, Phellinus gilvus and Phellinus baumii in Korea inhibited pulmonary inflammation, Phellinus rimosus (BERK) PILAT showed antitumor activity and anti-oxidant and antihepatotoxic activities, and Phellinus igniarius exerted antimutagenicity. Recently the mushroom cultivated in Cambodia with the shape of Phellinus linteus has been used for health and prevention of diseases as a remedy of folk. However, little was known on the characterization and biological response of the mushroom. Thus, with aqueous extract of Cambodian mushroom, the characterization of species by DNA analysis and anti-metastatic mechanism were evaluated in vitro and in vivo.